Examples of cancer-related biomarkers include tumor antigens, tumor mutation burden (TMB), or microsatellite instability (MSI). Since it is difficult to quantify the level of tumor neo-antigen, TMB and MSI can help to evaluate neo-antigen load. Additionally, physical characteristics of a tumor such as its inflammation can also serve as a predictive biomarker. In fact, tumor inflammation could indicate the activation of immune response and the infiltration of the tumor site by cytotoxic T cells.
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Metastatic #TNBC is classified by what is absent from the tumor. But in today’s #MeanstoMe, See Phan discusses how new targets and continued research in this area has advanced treatment options. #ASCO22 | Gilead Sciences
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