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  1. XIAFLEX® (collagenase clostridium histolyticum)

    XIAFLEX is a prescription medicine used to treat adult men with Peyronie's disease who have a "plaque" that can be felt and a curve in their penis greater than 30 degrees when treatment is …

  2. XIAFLEX® for Dupuytren's Contracture

    Learn about XIAFLEX®, a nonsurgical treatment option for Dupuytren's contracture. Read the full Prescribing Information, Medication Guide & more.

  3. How it Works | XIAFLEX® for Peyronie’s Disease

    XIAFLEX is a prescription medicine used to treat adult men with Peyronie’s disease who have a “plaque” that can be felt and a curve in their penis greater than 30 degrees when treatment is …

  4. About XIAFLEX® for Dupuytren's Contracture

    XIAFLEX® is an FDA-approved nonsurgical treatment for Dupuytren's contracture. Learn about how XIAFLEX® is injected, side effects, & how it may help.

  5. XIAFLEX® (collagenase clostridium histolyticum)

    In the XIAFLEX trials in Dupuytren’s contracture, 70% and 38% of XIAFLEX-treated patients developed an ecchymosis/contusion or an injection site hemorrhage, respectively.

  6. Preparation and Procedure | XIAFLEX® (collagenase clostridium …

    Find out how XIAFLEX® (collagenase clostridium histolyticum) works and how to prepare for injection and administration.

  7. Peyronie’s Disease | XIAFLEX® (collagenase clostridium histolyticum)

    Because of the risks of corporal rupture or other serious penile injury, XIAFLEX is available for the treatment of Peyronie’s disease only through a restricted program under a Risk Evaluation and …

  8. FAQs | XIAFLEX® for Peyronie’s Disease

    XIAFLEX is a prescription medicine used to treat adult men with Peyronie’s disease who have a “plaque” that can be felt and a curve in their penis greater than 30 degrees when treatment is …

  9. About Dupuytren’s Contracture | XIAFLEX® (collagenase …

    In the XIAFLEX trials in Dupuytren’s contracture, 70% and 38% of XIAFLEX-treated patients developed an ecchymosis/contusion or an injection site hemorrhage, respectively.

  10. XIAFLEX, along with a finger extension procedure, may help straighten or nearly straighten finger(s) afected by Dupuytren’s contracture and may improve range of motion after up to 3 …