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  1. Thiazolidinediones (TZDs): What They Are & Side Effects

    Thiazolidinediones (TZDs and glitazones) are a class of medications that treat Type 2 diabetes by improving insulin sensitivity, lowering glucose levels and helping reduce fat stored in your liver. …

  2. List of Thiazolidinediones (glitazones) - Drugs.com

    Thiazolidinediones (also called glitazones) are a class of medicines that may be used for the treatment of type 2 diabetes. They are a type of oral hypoglycemic (a medicine that lowers …

  3. Thiazolidinedione - Wikipedia

    Thiazolidinediones or TZDs act by activating PPARs (peroxisome proliferator-activated receptors), a group of nuclear receptors, specific for PPARγ (PPAR-gamma, PPARG).

  4. Thiazolidinediones: Uses, common brands, and safety info

    Mar 28, 2022 · Thiazolidinediones, or TZDs, help decrease blood glucose (sugar) levels by reducing insulin resistance and making the body respond to insulin. TZDs also reduce the …

  5. Thiazolidinediones - StatPearls - NCBI Bookshelf

    Feb 20, 2023 · Thiazolidinediones (TZDs), also called "glitazones," in managing type 2 diabetes can help with glycemic control and insulin resistance. There are 2 TZDs, rosiglitazone and …

  6. Mechanism of Action of Thiazolidinediones

    May 31, 2025 · Thiazolidinediones (TZDs), also known as glitazones, are oral antidiabetic drugs used to improve insulin sensitivity in patients with type 2 diabetes mellitus. Unlike insulin …

  7. Antidiabetics, Thiazolidinediones: Drug Class, Uses, Side ... - RxList

    Thiazolidinediones knew as “glitazones” are oral antidiabetic drugs used with a proper diet and exercise to control high blood sugar in people with type 2 diabetes mellitus (T2DM). Learn …

  8. TZD Drugs for Diabetes: How They Work, Uses, and Risks

    Jul 22, 2025 · Thiazolidinediones (TZDs) are a class of oral prescription medications used to manage type 2 diabetes. These drugs help control blood sugar levels in individuals whose …

  9. Thiazolidinediones - The Johns Hopkins Patient Guide to Diabetes

    These pills work primarily by enhancing the body’s ability to respond to insulin. When? Why? These medications typically lower A1c levels by 1 – 1.5%. When taken alone, these …

  10. Thiazolidinediones (TZDs) - Type2Diabetes.com

    Thiazolidinediones (TZDs) are drugs sometimes used to treat adults with type 2 diabetes (T2D). They control blood sugar levels by improving how your body uses insulin.