Background National and international guidelines recommend that psychosocial support should be a key component of the care offered to children and adolescents experiencing gender ...

Charts are presented which give centile standards for boys' and girls' heights at ages 2 to 9 when parents' height is allowed for. Mid-parent height is used (i.e. the average of father's and mother's ...

AIMS To evaluate the effects of discontinuing growth hormone (GH) treatment on energy expenditure and body composition, which might help predict those most likely to benefit from early reintroduction ...

Background We sought to measure the diagnostic accuracy of D-dimer in children with suspected pulmonary embolism (PE). Methods We queried our electronic medical record for quantitative D-dimer values ...

Objectives To provide up-to-date information on the use of long-term ventilation (LTV) in the UK paediatric population and to compare the results with data collected 10 and 20 years previously. Design ...

Introduction With approximately 50% of the drugs being prescribed off-label, the pediatric population is in need for an innovative approach to establish harmonized, best evidence-based dosing ...

Fibre is an essential nutrient in the human diet that is crucial for human health. It provides a range of functional benefits, including stool bulking, and physiological benefits through fermentation ...

Tell me how you measure me, and I will tell you how I will behave.Eliyahu Moshe Goldratt1 The pursuit of patient safety is a key component of the wider endeavour to improve quality of healthcare ...

Objective The ‘GP check’ at 6–8 weeks forms part of the selective surveillance system for developmental dysplasia of the hip (DDH) in the UK. It is imperative to pick up DDH within the first months of ...

Methods All children (under 16 year) who had a DMSA scan following UTI in 2007 (Jan-July) prior to the introduction of the NICE guidelines were identified, and compared with those undergoing DMSA ...

### Key practice points Childhood cancer treatment often impairs reproductive function and future fertility. Management requires assessment of fertility risk and consideration of fertility ...

This series of systematic reviews1–4 was commissioned by WHO in July 2022 to inform their guideline review process (www.who.int). The aim was to identify the current evidence for developing WHO ...