SANTA CLARA, Calif. — Quarterback Brock Purdy will miss his sixth straight start for the San Francisco 49ers with a toe ...

A young defense with lots of rookies or first-time starters lost stars Nick Bosa and Fred Warner for the entire season in ...

San Francisco 49ers quarterback Brock Purdy might be back in uniform for the first time in six weeks on Sunday against the ...

It’s not a 49ers quarterback controversy between Mac Jones and Brock Purdy before the Rams game — it’s protection.

The 49ers are preparing for a big divisional clash with the Rams Sunday and Brock Purdy could be active for the first time ...

The San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a knee ...

Kyle Shanahan has confirmed his final decision on who will be the starting quarterback for the 49ers in the NFC West showdown ...

Purdy already has led the 49ers to the NFC Championship Game, and he made a Super Bowl appearance in his first full season as ...

The San Francisco 49ers will start Mac Jones at quarterback against the Los Angeles Rams on Sunday while Brock Purdy continues to recover from his turf toe injury, according to ESPN's Adam Schefter.

The San Francisco 49ers' Week 10 injury report didn't have much good news for a handful of the team's starters.

If the 49ers continue winning with Mac Jones under center, Peter Schrager doesn't believe the team will go back to Brock Purdy as the starter.