The big day has finally arrived for Jay and Pamela. Both have a rare genetic disorder called osteogenesis imperfecta type 3 ...

The TLC stars were born with the same rare genetic condition and have broken more than 400 bones between them.

This year, the group is fundraising for Shriners Children's in Greenville, South Carolina.

For the last 12 years, the Alee Shriners in Savannah have been hosting an 'Iron Butt Ride' fundraiser. It's a 24-hour ...

Jay Manuel, 28, and Pamela Chavez, 30, were both born with a rare disorder called Osteogenesis Imperfecta Type III (OI).

How a 1981 episode of 'Mister Rogers' Neighborhood' opened kids' eyes to one boy's story — and now inspires a new character ...

Jeff Erlanger was a longtime fan of Fred Rogers before appearing on his show, and the two became friends for life ...

Ultragenyx's strong revenue growth, diverse streams, and late-stage pipeline make it a standout in rare disease and gene ...