The brain disease has most commonly been found in athletes in contact sports and others with a history of repeated brain trauma.

Shane Tamura, the Park Ave. gunman who killed an NYPD officer and three others before taking his own life, left behind a suicide note saying he suffered from CTE, a brain injury often linked to playing football, and was targeting the NFL — but took the wrong elevator, officials said Tuesday.

The 27-year-old man who shot and killed four people at a Midtown office building on Monday carried a note in his pocket, police sources told ABC News.