When a robust long-time patient with chronic pain and heavy alcohol use declines precipitously after a complicated hospital course, her medical team must find a way to revive her old self.

A new European Union regulation introduces a centralized clinical assessment process for comparing the effectiveness and safety of new medicines with those of the standards of care in various ...

Settlements of lawsuits against opioid manufacturers and other entities will shape drug policy for decades. Attention is needed to ensure that the funds will be dedicated to evidence-based activities.

A 4-year-old boy presented with fatigue and frequent falls. After falling, he could not stand up using his legs and would instead push himself up with his hands. The aminotransferase levels were ...

Whether screening with blood-based early-detection tests for multiple cancers in addition to usual care has clinical utility is unknown. In a randomized, controlled trial conducted in England, we ...

More evidence is needed to inform recommendations for intervals of colonoscopy surveillance after polyp removal. In this ...

Arterial Line Placement (Introduction) This video will demonstrate arterial line placement in the radial artery using two of the many techniques available for arterial line placement, an over-the-wire ...

Acute metabolic acidosis is common in hospitalized patients owing to conditions such as shock, kidney disease, and diabetic ketoacidosis. While the underlying cause is being treated, it may be ...

Tambotatug pelitecan (known as Tam-Peli, a new antibody–drug conjugate that targets the immune-checkpoint molecule B7-H3) showed promising clinical efficacy in patients with relapsed extensive-stage ...

In this prospective trial, patients with serrated polyps had a low 5-year risk of colorectal cancer (1.0%). Evelien Dekker can be contacted at [email protected]. The members of the EPoS Study Group ...

Hypertension is described as resistant if a patient who is taking three or more antihypertensive agents, including a diuretic, at the maximum recommended doses maintains a blood pressure of 140/90 mm ...

For a substantial minority of older adults, a stay in a post-acute care facility is the gateway into a cycle between the hospital and the nursing home that spans the final months of life. Certain M ...