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The dynamics of the pulmonary microbiome during mechanical ventilation in the intensive care unit and the association with occurrence of pneumonia

Rationale Ventilator-associated pneumonia (VAP) is the most common nosocomial infections in patients admitted to the ICU. The adapted island model predicts several changes in the respiratory ...
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Atypical adenomatous hyperplasia of the lung: a clinicopathological study of 118 cases including cases with multiple atypical adenomatous hyperplasia

a Pathology Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan, b Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan Dr A Ochiai, ...
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Validation of predictive rules and indices of severity for community acquired pneumonia

Background: A study was undertaken to validate the modified American Thoracic Society (ATS) rule and two British Thoracic Society (BTS) rules for the prediction of ICU admission and mortality of ...
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Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease

Academic Unit of Respiratory Medicine, St Bartholomew’s and Royal London School of Medicine and Dentistry, London EC1A 7BE, UK Correspondence to: Professor J A Wedzicha, Academic Unit of Respiratory ...
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The study of human sleep: a historical perspective

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Paradoxical reactions during tuberculosis treatment in patients with and without HIV co-infection

1 Department of Thoracic and HIV Medicine, Royal Free Hospital, London, UK 2 Department of Infectious Diseases, Royal Free Hospital, London, UK 3 Department of Primary Care and Population Sciences, ...
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Respiratory disease associated with solid biomass fuel exposure in rural women and children: systematic review and meta-analysis

Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada Correspondence to Chris Carlsten, Department of Medicine, The University of British Columbia, Vancouver ...
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Obesity and the lung: 5 · Obesity and COPD

Department of Human Biology, Nutrition and Toxicology Research Institute (NUTRIM), Maastricht University, Maastricht, The Netherlands Dr A M W J Schols, NUTRIM School for Nutrition, Toxicology and ...
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Prevalence, diagnosis and relation to tobacco dependence of chronic obstructive pulmonary disease in a nationally representative population sample

1 Cancer Research Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK 2 Division of Epidemiology and Public Health, University of ...
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Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation

Background Early detection of lung cancer saves lives, as demonstrated by the two largest published low-dose CT screening trials. Optimal implementation depends on our ability to identify those most ...
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Animal models of chronic obstructive pulmonary disease

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A UK-based resource to support the monitoring and safe use of anti-TB drugs and second-line treatment of multidrug-resistant TB

Using the best available evidence and expert consensus, this document provides guidance for adverse effect monitoring in multidrug-resistant TB (MDR-TB). It includes recommendations for baseline tests ...