A peer-reviewed neurology, neurosurgery and psychiatry journal publishing the latest research and reviews on the entire genre of neurological sciences.

Background The diagnosis of dementia with Lewy bodies (DLB) is based on diagnostic clinical criteria, which were updated over the years. Objective To evaluate, through a systematic review, accuracy of ...

A systematic review and meta-analysis were conducted to quantify the efficacy of transcranial magnetic stimulation (TMS) and electroconvulsive therapy (ECT) for the treatment of motor dysfunction in ...

Objectives: To examine the relative relapse-rate patterns over time in a relapsing multiple sclerosis (MS) cohort and to investigate potential predictors of relapse rates and periods of low-relapse ...

OBJECTIVE To test the feasibility and validity of the EQ-5D (a widely used generic (disease non-specific) quality of life (QoL) instrument which allows comparisons between different patient groups and ...

Background Age of onset of multiple sclerosis (MS) peaks in the 3rd and 4th decades and is rarely less than 18. Robust longitudinal studies in paediatric-onset MS (POMS) are limited, and a clearer ...

OBJECTIVE To evaluate physical activity as a risk factor for subarachnoid haemorrhage. METHODS A population based case-control study in King County, Washington. A standardised, personal interview was ...

Background The link between low-density lipoprotein cholesterol (LDL-C) levels and dementia risk is poorly understood, with conflicting evidence on the role of LDL-C and the impact of statin therapy ...

Background Oral anticoagulation (OAC) effectively reduces stroke risk in patients with atrial fibrillation (AF), but its use after intracranial haemorrhage (ICH) remains controversial due to bleeding ...

Parkinson’s disease seems to occur more commonly in men than women based primarily on studies of death rates and prevalence. In recent years, several population based incidence studies of Parkinson’s ...

Background Ultra-processed foods (UPFs), widely consumed globally, are increasingly recognised as a key factor in poor dietary quality and diet-related health risks. However, little is known about the ...

Parkinsonian syndromes are characterised by slowness of initiation (akinesia), movement (bradykinesia), and thought (bradyphrenia), tremor at rest (3–5 Hz) and on posture (4–8 Hz), and extrapyramidal ...