Background Neutrophils guarantee a prompt and robust host response to pathogens. Yet, overshooting neutrophil activation ...

Liver fibrosis represents a serious worldwide health issue with a prevalence of around 5% in general populations.1 The most ...

Introduction There is increasing evidence for the use of probiotic bacteria in the treatment of irritable bowel syndrome (IBS). Most reports to date have been in patients with diarrhoea or bloating.

2 Department of Clinical Biochemistry, Dalian Medical University, Dalian, China 3 Department of General Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China 4 Institutes ...

12 Liver Clinic, Toronto Western & General Hospital, University Health Network, Toronto, Ontario, Canada Correspondence to Professor H L A Janssen, University of Toronto & Erasmus University Rotterdam ...

Cyclooxygenase (COX), the key enzyme for synthesis of prostaglandins, exists in two isoforms (COX-1 and COX-2). COX-1 is constitutively expressed in the gastrointestinal tract in large quantities and ...

Background:During the process of tumorigenesis most colon cancer cells acquire resistance to apoptosis. The short chain fatty acid butyrate is well established as an antitumour agent which selectively ...

BACKGROUND Use of the conventional Western and Japanese classification systems of gastrointestinal epithelial neoplasia results in large differences among pathologists in the diagnosis of oesophageal, ...

a Department of Psychosomatic Medicine, b Department of Comprehensive Medicine, Tohoku University School of Medicine, Sendai, Japan Dr S Fukudo, Department of Psychosomatic Medicine, Tohoku University ...

a Department of Surgery, University of Heidelberg, Heidelberg, Germany, b Department of Immunochemistry, German Cancer Research Center, Heidelberg, Germany Dr B Sido, Department of Surgery, University ...

Background Existing scales for assessing faecal incontinence have not been validated against clinical assessment, or with regard to reproducibility. They also fail to take into account faecal urgency, ...

5 The Institute of Food Research and University of East Anglia, Norwich, UK Correspondence to Professor Simon R Carding, Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK ...