Gut

Loss of sinusoidal endothelial identity: RAP1A at the crossroads of capillarisation and liver fibrosis

Liver fibrosis represents a serious worldwide health issue with a prevalence of around 5% in general populations.1 The most ...
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The probiotic VSL#3 increases scbm and reduces symptom severity scores in patients with functional constipation

Introduction There is increasing evidence for the use of probiotic bacteria in the treatment of irritable bowel syndrome (IBS). Most reports to date have been in patients with diarrhoea or bloating.
gut.bmj

Novel roles of liver sinusoidal endothelial cell lectin in colon carcinoma cell adhesion, migration and in-vivo metastasis to the liver

2 Department of Clinical Biochemistry, Dalian Medical University, Dalian, China 3 Department of General Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China 4 Institutes ...
gut.bmj

Cyclooxygenase 2—implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives

Cyclooxygenase (COX), the key enzyme for synthesis of prostaglandins, exists in two isoforms (COX-1 and COX-2). COX-1 is constitutively expressed in the gastrointestinal tract in large quantities and ...