BMJ

Purine-rich foods intake and recurrent gout attacks

1 Clinical Epidemiology Research and Training Unit, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA 2 Data Coordinating Center, Boston University School of ...
BMJ

Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group

20 Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, The Netherlands Correspondence to Dr Robert G W Lambert, Department of Radiology and Diagnostic Imaging, University ...
BMJ

Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores

2 Rheumatology Department, Leiden University Medical Center, Leiden, The Netherlands 3 Rheumatology Department, Maastricht University Medical Center, Maastricht, The Netherlands Background The ...
BMJ

EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis

15 Department of Radiology. Leiden University Medical Centre, Leiden, The Netherlands 16 Department of Rheumatology and Clinical Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands ...
BMJ

AB1069 URIC ACID LEVELS IN RELATION TO FASTING BLOOD GLUCOSE AND HbA1c

2 Farhat Hached Hospital, Endocrinology and Diabetes Department, Sousse, Tunisia Background Hyperuricemia is reported to be a risk factor for the development of type 2 diabetes (T2D) and prediabetes.
BMJ

OP0039 ALPN-303, AN ENHANCED, POTENT DUAL BAFF/APRIL ANTAGONIST ENGINEERED BY DIRECTED EVOLUTION FOR THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS ...

1 Alpine Immune Sciences, Translational Sciences, Seattle, United States of America 2 Alpine Immune Sciences Inc, Immunology, Seattle, United States of America 3 Alpine Immune Sciences Inc, Clinical ...
BMJ

POS1128 COMBINATION TREATMENT OF AR882, A NEW URAT1 INHIBITOR, AND XANTHINE OXIDASE INHIBITORS ALLOPURINOL OR FEBUXOSTAT: EFFECT ON URIC ACID ...

Background: Xanthine oxidase inhibitors (XOI) are commonly used as urate lowering therapy (ULT) for the treatment of gout. Allopurinol, the first-line treatment, demonstrates low response rate (< 40%) ...
BMJ

OP0224 RESULTS OF A PHASE 2 STUDY OF RG6125, AN ANTI-CADHERIN-11 MONOCLONAL ANTIBODY, IN RHEUMATOID ARTHRITIS PATIENTS WITH AN INADEQUATE RESPONSE TO ...

Background Cadherin-11 is expressed on fibroblasts in joints of RA patients and augments local fibroblast–mediated inflammation, pannus formation and tissue invasion (1). RG6125 is a novel humanized ...
BMJ

Pneumococcal antibody levels after pneumovax in patients with rheumatoid arthritis on methotrexate

1 Department of Medicine and Rheumatology, Queen Elizabeth Hospital, Gateshead, UK 2 Department of Immunology, Queen Elizabeth Hospital, Gateshead, UK Correspondence to Clive Kelly, Department of ...
BMJ

OP0293 ANTI-CITRULLINATED HISTONE MONOCLONAL ANTIBODY CIT-013, A DUAL ACTION THERAPEUTIC FOR NEUTROPHIL EXTRACELLULAR TRAP ASSOCIATED AUTOIMMUNE DISEASES

Background Neutrophil extracellular traps (NETs) contribute to the pathophysiology of multiple inflammatory and autoimmune diseases. Targeting the NETosis pathway has demonstrated significant ...
BMJ

AB0757 EULAR/ACR diagnostic and classification criteria of systemic vasculitis (DCVAS) study update

Background Patients with vasculitis typically present with non-specific features, such as fever, fatigue and myalgia all of which are also common among different diseases. One of the aims of this ...