The 49ers are preparing for a big divisional clash with the Rams Sunday and Brock Purdy could be active for the first time since Week 4.

San Francisco 49ers quarterback Brock Purdy might be back in uniform for the first time in six weeks on Sunday against the Los Angeles Rams, but not as the starter, coach Kyle Shanahan said Friday.

Sunday, in the media room at MetLife Stadium, where the New York Jets, the New York Giants and NFL players’ ACLs go to die each week, San Francisco 49ers head coach Kyle Shanahan subtly gave the most revealing update on quarterback Brock Purdy’s lingering toe injury.

If the 49ers continue winning with Mac Jones under center, Peter Schrager doesn't believe the team will go back to Brock Purdy as the starter.

ESPN analyst Dan Orlovsky floated the possibility Brock Purdy may not get his starting job back from Mac Jones once he's healthy.

Brock Purdy hasn't suited up since late September because of a turf toe injury, but San Francisco 49ers head coach Kyle Shanahan said he doesn't expect the injury to keep Purdy out for the rest of the season.

Injuries are a significant factor in the results of NFL action every week, and that certainly will be the case in Week 10 as the 2025 NFL season hits the back nine weeks of the regular season. There are several notable names whose statuses are unknown for this upcoming Week 10 slate,

The San Francisco 49ers announced a practice decision regarding quarterback Brock Purdy as the team prepares for Week 10.

NFL media insider Tom Pelissero reports that San Francisco 49ers quarterback Brock Purdy is listed as questionable for the Week 10 matchup vs. the Los Angeles Rams.

The San Francisco 49ers face a slew of injuries, including to their starting quarterback, but manage to put together wins anyway. Brock Purdy missed seven games due to a turf toe injury, leaving former first rounder Mac Jones leading the offense for the majority of the season.