Previous research has revealed that the Apolipoprotein-ε4 (APOE-ε4) allele increases the risk for a variety of diseases in aging populations, specifically Alzheimer's and cardiovascular disease. And ...

Study findings suggest that a single APOL1 risk allele can confer risk of kidney disease. West African individuals with just 1 allele variant in the APOL1 gene are at increased risk for chronic kidney ...

The brain is a special organ, and immune cells there called microglia work to repair damage and maintain the health of neural networks. About ten percent of brain cells are estimated to be microglia, ...

A new genetic variant has been uncovered that may protect individuals at high risk from developing Alzheimer’s disease. Researchers at Columbia University found that this gene can reduce one’s risk by ...

As the strongest risk factor for Alzheimer’s disease, ApoE4 has a bad reputation, and rightly so. Yet shade thrown on ApoE4 may be obscuring the inconvenient truth that ApoE3 isn’t so innocent, either ...

SAN DIEGO -- APOL1 genotypes associated with high risk for chronic kidney disease (CKD) were common among individuals living in West Africa, suggesting a mechanism at play in the high rates of kidney ...