Funding: This work was supported by Columbia University Dean’s Office Fund and Columbia University Translational Therapeutics (TRx) Pilot Award (to M.Y.). The funders had no role in study design, data ...
The wiggly ‘tail’ at the end of the coronavirus envelope protein could help explain why some coronavirus diseases are more virulent than others, a young African researcher has found. Once considered a ...
In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...
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Key human proteins that power coronavirus replication point to new treatment strategies
Despite vaccines and treatments, SARS-CoV-2—the virus that causes COVID-19—continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still ...
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A potential broad coronavirus drug target: Blocking tRNA-modifying enzymes slows viral proteins
Coronaviruses not only use the machinery of the human cells they infect: they modify them to achieve optimal conditions to produce viral proteins and thus spread more quickly. This is the main ...
In a recent study published in the journal Nature, researchers use cryogenic electron microscopy (cryo-EM) in tandem with molecular dynamics simulation to reveal that the usually closed spike proteins ...
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