More than 35,000 men in the United States die from prostate cancer each year. Now, a new study reveals the immune cell ...

Correspondence to Professor Wael El-Rifai, Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA; wxe45{at}miami.edu; Dr Heng Lu; heng.lu{at}med.miami.edu Objective Chronic ...

Skeletal muscle regeneration depends on muscle stem cells (MuSCs), in which cadherin-mediated adhesion and planar cell polarity (PCP) signaling play critical roles. M-Cadherin is the major cadherin ...

ABSTRACT: The objective of this study was to determine the distribution pattern of E-cadherin in parthenogenetic sheep embryos (Ovis aries) and its relationship with fragmentation. Mature oocytes were ...

SHANGHAI, Sept. 23, 2024 /PRNewswire/ -- On September 14, 2024, BioCity presented interim clinical results on the safety and efficacy of its first-in-class antibody-drug conjugate (ADC) BC3195 ...

Introduction: Proteolysis of vascular endothelial (VE)-cadherin is a biomarker for disruption of endothelial cell (EC) barrier function, with elevated levels of soluble VE-cadherin associated with ...

Cadherin-catenin complexes are integral components of the adherens junctions crucial for cell-cell adhesion and tissue homeostasis. Dysregulation of these complexes is linked to cancer development via ...

Our bodies comprise different tissues and organs, which are composed of many cells that must adhere to form functional higher order structures. This adherence is facilitated by specialized proteins ...

Breathing, and the motor circuits that control it, is essential for life. At the core of respiratory circuits are Dbx1-derived interneurons, which generate the rhythm and pattern of breathing, and ...

Decision letter after peer review: Thank you for submitting your article "Coordinated cadherin functions sculpt respiratory motor circuit connectivity" for consideration by eLife. Your article has ...