Spironolactone, an aldosterone blocker, compared with placebo, did not show any significant improvement in terms of heart failure (HF) hospitalizations and cardiovascular death at 24 months in ...

Health care professionals should explore the use of glucagon-like peptide-1 receptor agonists (GLP1RAs) for cardiovascular risk reduction and their broader impacts on cardiometabolic health beyond ...

The U.S. Food and Drug Administration (FDA) has approved baxdrostat, a first-in-class oral aldosterone synthase inhibitor, as an add-on therapy for hypertension in adults whose blood pressure (BP) is ...

Chronic consumption of high levels of caffeine a day can lead to an increase in high heart rate and blood pressure that persists after resting from a step test, increasing the risk of cardiovascular ...

Silent atherosclerosis is detectable using imaging in early adulthood, with age- and sex-associated increases in prevalence across arterial territories and significant increases in plaque volume, ...

Lowering LDL-C to <55 mg/dL in patients with atherosclerotic cardiovascular disease (ASCVD) reduced the rate of major cardiovascular events by one-third, according to the Ez-PAVE trial presented ...

Device-based left atrial appendage (LAA) closure was comparable to non-vitamin K antagonist oral anticoagulant (NOAC) therapy in reducing the combined rate of death from cardiovascular causes, stroke, ...

Alpha-Gal Syndrome (AGS) is an underrecognized, tick-borne allergic condition with emerging relevance in cardiovascular medicine. Sensitization to galactose-α-1,3-galactose (alpha-gal), a ...

In TAVI PCI, which was simultaneously published in NEJM, a strategy of TAVI before PCI was noninferior to a PCI-first strategy in patients with severe aortic stenosis and concomitant coronary artery ...

In patients with acute, intermediate-risk pulmonary embolism (PE), ultrasound-facilitated, catheter-directed fibrinolysis plus anticoagulation led to a lower risk of PE-related death, cardiopulmonary ...

A treatment-induced increase in plasma potassium levels reduced the risk of ventricular arrhythmias, in patients with ICDs and baseline plasma potassium levels of 4.3 mmol per liter or lower, based on ...

Vessel fractional flow reserve (vFFR)-guided revascularization was noninferior to pressure-wire-based fractional flow reserve (FFR)-guided revascularization in patients with intermediate coronary ...