Objective Fatigue is a common, multifaceted symptom in SLE which is difficult to treat. There has been a lack of broadly ...

Objective We aimed to characterise differences in the occurrence of maternal cardiovascular events (CVEs) and adverse ...

Objectives DNASE1L3 deficiency is a rare monogenic cause of early-onset SLE and hypocomplementaemic urticarial vasculitis ...

Background Global collaboration is a key driver of advances in complex diseases such as lupus, yet its distribution and ...

The association between SLE and composite stroke, ischaemic stroke and haemorrhagic stroke remains incompletely understood. This meta-analysis aims to assess the risk of stroke in patients with ...

Objective Renal flares in patients with systemic lupus erythematosus (SLE) result in significant nephron loss. Thus, identification of reliable early signals of impending renal flares is anticipated ...

Objective Identify whether changes in metabolite abundance are associated with SLE flare remission and changes in DNA methylation (DNAm). Methods 40 multiethnic patients with SLE were recruited during ...

Introduction Lupus nephritis (LN) exhibits substantial clinical and pathological heterogeneity. We aimed to define proteomics-based molecular subtypes of LN and identify candidate biomarkers for ...

Objective To assess the appropriateness of expanded serological activity eligibility criteria for belimumab use in the UK systemic lupus erythematosus (SLE) population (and possibly other countries), ...

Objective To develop an improved score for prediction of severe infection in patients with systemic lupus erythematosus (SLE), namely, the SLE Severe Infection Score-Revised (SLESIS-R) and to validate ...

Infectious agents especially viruses e.g. Epstein Barr virus contribute to systemic lupus erythematosus (SLE) pathogenesis and can trigger lupus disease activity by driving autoimmunity through ...

Objective To characterise the safety and efficacy of anifrolumab in active lupus nephritis (LN) through year 2 of the phase II randomised, double-blind Treatment of Uncontrolled Lupus via the ...