Gastrulation is a process common to nearly all metazoan organisms during which an embryo with distinct tissue layers develops out of a seemingly unstructured assembly of cells referred to as 'blastula ...

A collaboration of researchers from Japan, Spain and the U.S. offers a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop ...

With the construction of a building, one of the first steps before creating the upright structure is to set the foundations and the floorplan. Mammalian development is not so different. A ...

It’s one of life’s most defining moments—that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for ...

Scientists from Helmholtz Zentrum München revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has ...

Molecular and cellular mechanisms of epithelial–mesenchymal transition (EMT), crucial in development and pathogenesis, are still poorly understood. Here we provide evidence that distinct cellular ...

Materials scientists at UNSW Sydney have shown that human pluripotent stem cells in a lab can initiate a process resembling the gastrulation phase – where cells begin differentiating into new cell ...

Gastrulation is one of the most intensely studied biological processes. During gastrulation, animal embryos undergo tissue flows and folding events that transform a simple monolayer of cells into a ...

In their publication in Science, Professor Guojun Sheng (Kumamoto University, Japan), Professor Alfonso Martinez Arias (Universidad Pompeu Fabra, Spain) and Professor Ann Sutherland (University of ...