Chronic pain is one of the most common and expensive health problems in the nation, affecting an estimated one in five U.S.

Anxiety-related disorders can have a profound impact on the mental health and quality of life of affected individuals. Understanding the neural circuits and molecular mechanisms that trigger anxiety ...

The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, ...

Depression is a condition affecting millions across the globe. However, efficient drugs with minimal adverse effects are scarce. Now, researchers have reported how KNT-127, a delta opioid receptor ...

Researchers from Tokyo University of Science uncover cellular and molecular mechanisms underlying the antidepressant-like effects of the delta opioid receptor agonists, paving the way for its clinical ...

One of the greatest revolutions in the field of pain medication was the isolation of morphine from the opium poppy in the 19th century. Morphine molecules act as painkillers by attaching themselves to ...

Researchers have observed that the length of daylight hours impacts opioid receptor levels in brown fat. When daylight hours shorten, the receptor activity levels elevate. A similar phenomenon also ...

Substances that activate adrenaline receptors as opposed to opioid receptors have similar pain-relieving properties to opioids minus the negative side effects. The corresponding study was published in ...