Methodology that is not complete, as well as discrepancies regarding the proposed mode of action of lipoxin A4, are significant weaknesses.

New findings suggest a way to disarm resistant bacteria, making existing antibiotics effective and improving treatment options for people with hard-to-treat infections.

New findings suggest sideways walking in crabs is a rare but innovative trait originating from a common ancestor, and provide a framework for understanding how animal locomotion diversifies and ...

A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.

Graph theory and computational modeling reveal that neural network architecture biases the male Caenorhabditis elegans brain toward prioritized sexual behaviors.

In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...

Modality-agnostic decoders leverage modality-invariant representations in human subjects' brain activity to predict stimuli irrespective of their modality (image, text, mental imagery).

The formation of protein amyloid fibrils in the brain is a hallmark of various neurodegenerative diseases, including Alzheimer diseases and Parkinson diseases. Amyloid f ...

A new biologically-informed training paradigm enables protein language models to predict affinity maturation trajectories for antibodies.

Homozygous but not heterozygous loss of Pten in sporadic mouse models of SHH-medulloblastoma greatly accelerates tumor formation, not metastasis, through increased survival of differentiated cells and ...

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...

This paper provides a valuable observation that imiquimod, a compound often used to induce a psoriasis-like skin inflammation in mice, has a TLR7-independent effect acting through the unfolded protein ...