San Francisco 49ers wide receiver Brandon Aiyuk is likely itching to get back on the field after suffering a season-ending injury in Week 7 last season, but he and the team may have broken an NFL rule as he works his way back from a torn ACL and MCL.

There's no clarity yet on which quarterback will start for the San Francisco 49ers in their final preseason game.

The 49ers have committed to Brock Purdy with a big extension. But the key to that deal is the guy standing behind him in the backfield.

San Francisco 49ers head coach Kyle Shanahan believes the locker room vibes are much better compared to last season. Aside from the constant injuries leading up to the looming 53-man roster decision, a lot has changed in San Francisco.

Bitter rivals clash as the San Francisco 49ers and the Las Vegas Raiders go head-to-head in Week 2 of the NFL preseason today.

NBC Sports NFL commentator Michael Holley has major concern for San Francisco 49ers over Christian McCaffrey entering 2025 season.

The San Francisco 49ers already lean heavily on two seventh-round picks, now they may have another in their starting lineup.

Las Vegas Raiders rookie running back Ashton Jeanty ran over a San Francisco 49ers defender in a highlight-reel moment in his second preseason game.

With the regular season right around the corner, Week 3 of the preseason serves as the last chance for teams to prove themselves and settle position

Now comes USA Today’s Jacob Camenker with an option for the 49ers to explore – a trade for Washington Commanders running back Brian Robinson Jr. “The 49ers have a great lead back in Christian McCaffrey, but they could use depth behind the 29-year-old star,” Camenker wrote.