In this episode of C&EN Uncovered, host Craig Bettenhausen speaks with C&EN senior editor Laurel Oldach about a laser phase ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

Hosts of new applications have turned the light microscope into an exquisitely sensitive measuring device that can be used to image dynamic cellular events right down to the molecular level. Indeed, ...

A computer-assisted design schematic showing how an electron beam is routed within a microscope. After going through the sample, it crosses a bright cyan beam representing the laser beam. A schematic ...

a, An axi-symmetric binary phase filter (BPF) and image reconstruction network are jointly learned through the physics-informed neural network. The learned BPF is fabricated and inserted in a pupil ...