Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

In 1997, Sanger, Nicklen and Coulson described a method for determining DNA nucleotide sequences. 1 Nearly five decades later, Sanger sequencing remains an entrenched technology for targeted ...

Whether you’re interested in why a living system works as it does or the reasons it goes awry, proteins are a critical part of the molecular picture. The proteins circulating in a person’s plasma can ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...