In a recent review published in Pharmaceuticals, researchers documented the various polymeric materials that can be used to synthesize micelles, which can then be used for targeted cancer therapy by ...
Olaparib is a selective poly (ADP-ribose) polymerase inhibitor. However, its clinical application is hindered by low solubility and undesired pharmacokinetic profiles (e.g., relatively short ...
December 7, 2022 / Kawasaki, JAPAN: Innovation Center for NanoMedicine (iCONM; Center Director: Prof. Kazunori Kataoka), a research institute of the Kawasaki Institute of Industrial Promotion (KIIP), ...
Substituting amines with phosphonium-based cations could greatly improve the performance of mRNA-loaded polymeric micelles, report scientists. By adopting this innovative strategy, they managed to ...
Poloxamer 407 self-assembles into micelles in solution and turns into a gel at around body temperature. This study revealed important differences in how these micelles interact and organize into gels ...
The effect of ctDNA tumor fraction (TF) on overall survival and concordance between tissue genomics and ctDNA in Lung-MAP.
Researchers from TU Delft have found a new method to efficiently make nano carriers loaded with radioactive salts for both imaging and treatment. Because the assembly of these nano carriers is ...
Polymeric nanoparticles are nanoscale-sized objects constructed from polymers such as polyethylene glycol (PEG) or polylactide-co-glycolide (PLGA), with applications in the in vitro delivery of ...
Micelle-forming polymers such as poloxamer 407 (P407) are promising drug nanocarriers, yet their sol–gel transition under physiological conditions remains poorly understood. In a recent study, ...
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