SportsLine's projection model, which is on a red-hot 17-5 run on all top-rated MLB picks, has locked in its 'Sunday Night Baseball' predictions for the Chicago Cubs vs. San Francisco Giants

Our Orioles vs. Blue Jays predictions expect Jesus Sanchez to do some damage in a favorable matchup against Shane Baz.

The Cincinnati Reds (31-30) are headed to Busch Stadium on Sunday where they will compete against the St. Louis Cardinals (32-28). The moneyline on this game has Cincinnati at -128 and St. Louis is coming in at +106. The over/under is set at 9. The starting pitchers will be Rhett Lowder and Michael McGreevy.

SportsLine's model simulated Seattle Mariners vs. Detroit Tigers 10,000 times and revealed its MLB picks for Saturday's matchup

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The New York Yankees (37-26) are on their way to Progressive Field on Monday where they will go up against the Cleveland Guardians (36-29). The odds on this game have New York at -128 while Cleveland is at +106. The over/under has been set at 9. The men taking the mound are Cam Schlittler and Joey Cantillo.

The MLB schedule on Friday, June 5 features all 30 teams in action, headlined by the start of a three-game series between the Boston Red Sox and New York Yankees, the Freeway Series between the Los Angeles Angels and Los Angeles Dodgers and the San Diego Padres trying to snap a five-game skid when they host the New York Mets.

Get the best Angels vs. Dodgers predictions ahead of Saturday's matchup in Chavez Ravine. Free MLB picks for June 6.