More than half-a-century after the fact, it’s still the look in his father’s eyes that John Langerhans remembers. It was a look that led Langerhans to a lifetime of playing and coaching baseball, ...

Some people might say that Paul Langerhans Jr. was destined to make many contributions to medicine because he was born into a family of physicians and scientists. He made his first major contribution ...

The occurrence of graft-versus-host disease (GVHD) in the skin of patients receiving bone-marrow transplants is a common and serious complication, hindering the widespread use of this procedure.

A nationwide team led by researchers at Baylor College of Medicine, Texas Children’s Hospital and UPMC Children's Hospital of Pittsburgh has proposed a major revision to how Langerhans cell ...

In contrast to most dendritic-cell populations, Langerhans cells repopulate locally throughout life in the steady state, independently of any input from the blood circulation. In contrast to quiescent ...

Positron-emission tomographic (PET) images show a single bone lesion involving the humerus (Panel A, arrow); low-risk lesions involving the orbit, lymph nodes, bone (multifocal lesion), and thymus ...

Pulmonary Langerhans'-cell histiocytosis is an uncommon interstitial lung disease in adults. It has an unpredictable course and may be associated with an increased susceptibility to the development of ...

Researchers at Yale School of Medicine have demonstrated that Langerhans cells in the skin, which had been thought to alert the immune system to pathogens, instead dampen the skin's reaction to ...

We report an unusual case of Langerhans cell granulomatosis (LCG) manifested as a villous synovial proliferation in a 38-year-old female jogger. One year after the onset of joint symptoms, she had a ...

Fifty-four patients from 12 countries took VMF 20 mg/kg/d. They were classified according to risk organ involvement: liver, spleen, and/or blood cytopenia. The main evaluation criteria were adverse ...

Researchers found that Langerhans cells (LCs) play a crucial role in mucocutaneous acute guest-versus-host disease (aGVHD). Their experiments in mice showed that when the LCs of a recipient were ...

Langerhans cell histiocytosis (LCH) is a rare condition characterized by abnormal growth of the Langerhans cells. The proliferation of these cells leads to the formation of tumors called granulomas, ...