If you're the motor protein up front, be prepared to do the heavy pulling. That's one conclusion from a Rice University-led study of the mechanisms that drive kinesins, motor proteins that carry cargo ...

Prospective multicentric trial evaluating prognostic and predictive value of circulating tumor cells in first-line chemotherapy metastatic breast patients. Impact of high-risk classification by FISH ...

Kinesins are molecular motor proteins that use energy from the hydrolysis of adenosine triphosphate (ATP—a universal store of energy in all cells), and function in various cellular processes. They are ...

Multiple kinesins are involved in efficient production of male gametes and deletion of kinesin genes halts parasite transmission, a discovery that can be explored further for drug discovery. "In ...

Microtubule motor proteins can be either plus end motors or minus end motors depending on the direction of movement. Mitosis requires the trafficking of proteins along microtubules to produce two ...

One of the hallmarks of cancer is the uncontrolled growth of cells that leads to tumours forming. Using chemotherapy that disrupts the machinery needed for cell division is commonly used to tackle ...

Simulations detail the mechanisms of kinesins that carry cargo inside cells. Scientists have determined the motor proteins respond best to strong forces and hardly at all to weak ones, even those ...