Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

Researchers have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual ...

Real image of DNA molecules being copied in human cells, visualized by immunofluorescence microscopy. The yellow arrows mark where replication begins, and the white arrows indicate the direction in ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

Genomic heterogeneity has largely been overlooked in single-cell replication timing (scRT) studies. Here, we develop MnM, an efficient machine learning-based tool that allows disentangling scRT ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

The Polymerase Chain Reaction (PCR) is a technique for the amplification of DNA in vitro (this describes experiments with cells outside their normal environment). PCR amplifies DNA using complementary ...