Extracellular signals are relayed to the cell’s interior by second messengers such as cyclic AMP (cAMP), which was once thought to diffuse freely throughout the cytoplasm. Yet cAMP has also become ...

Gradient mapping is an important technique to summarize high dimensional biological features as low dimensional manifold representations in exploring brain structure-function relationships at various ...

Patients with major depressive disorder (MDD) exhibit concurrent deficits in both sensory and higher-order cognitive processing. Connectome studies have suggested a principal primary-to-transmodal ...