Please provide your email address to receive an email when new articles are posted on . Hepatocellular carcinoma, the sixth most common cancer, accounts for 90% of primary liver cancers worldwide. Its ...

TACE/ADAM17 is a transmembranous protease that cleaves membrane-bound growth factors like EGFR ligands. TACE-dependent proteolysis is regulated by its inhibitor, tissue inhibitor of metalloproteinases ...

The efficacy of transarterial techniques can be assessed in terms of imaging response (CT scan), biologic response (AFP), degree of tumor necrosis, patient survival or quality of life. The most ...

Transarterial chemoembolization (TACE), a minimally invasive procedure for liver cancer, is an effective treatment strategy for patients with large, asymptomatic, or multifocal hepatocellular ...

Prion and Alzheimer's disease are neurodegenerative disorders characterized by the accumulation of plaques containing misfolded PrP Sc and Aβ, respectively 1,2. Neurotoxic and aggregation-prone Aβ ...

Combining TACE and SBRT offers a promising treatment for large HCC tumors, addressing TACE's limitations in intermediate-stage cases. Technological advancements have improved SBRT's precision and ...

Adding Imfinzi and Avastin to transarterial chemoembolization led to a 23% reduction in the risk of progression or death in patients with liver cancer. Patients with unresectable hepatocellular ...

Transarterial chemoembolization (TACE) is a type of treatment for liver cancer. It works by delivering chemotherapy drugs directly to the tumor and blocking its blood supply. Liver cancer occurs when ...

Randomized phase II trial of TACE plus everolimus as first-line therapy in localized unresectable hepatocellular carcinoma (HCC): The TRACER trial. Background: TACE is regarded as the standard of care ...

Abbreviations: AP, activator protein; HFSR, hand-foot-skin reaction; INR, international normalized ratio. Each patient experienced at least one toxicity during subsequent weeks of cycle one (sorafenib ...

Tick marks indicate censoring of data. No participants had an albumin-bilirubin grade of 3, so this group has not been included in subgroup definitions here. BCLC=Barcelona Clinic Liver Cancer.

Transarterial chemoembolization (TACE) improves survival in cirrhotic patients with hepatocellular carcinoma (HCC). The optimal schedule, best anticancer agent and best technique are still unclear.