Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural network (CNN) with ...
Researchers from Tokyo Metropolitan University have developed a suite of algorithms to automate the counting of sister chromatid exchanges (SCE) in chromosomes under the microscope. Conventional ...
Sister chromatid exchanges (SCEs) occur when identical chromatids swap segments during or after DNA replication, serving as sensitive markers of DNA repair and chromosomal integrity. These reciprocal ...
During meiosis, sister chromatids produced by chromosome duplication are held together by Rec8, a meiosis-specific cohesion protein. Rec8 joins the whole length of the sister chromatids together, and, ...