Influenza A virus dismantles paraspeckles, small RNA-scaffolded structures inside the cell nucleus, to suppress antiviral ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more vulnerable to diseases and infections. Once inside human cells, HIV ...

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

Direct interactions between the cell’s powerhouses and nuclear pores might channel energy straight into the nucleus, fuelling cell division and differentiation. Menendez-Montes et al. investigated ...

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

For decades, biologists assumed a cell's energy simply diffused to wherever it was needed. It turns out the most important destination of all has a private delivery line. Subscribe to our newsletter ...

The artificial cell nucleus (right) constructed using the purified DNA was morphologically very similar to the natural cell nucleus derived from an egg (left). A team led by Professor Kazuo Yamagata ...