49ers host Matthew Stafford and the Rams

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49ers-Rams roundtable: Who's stopping Matthew Stafford? Can S.F. pull off the upset?
The Chronicle's coverage team weighs in as the San Francisco 49ers (6-3) are preparing to host their division-rival Los Angeles Rams (6-2) in a rematch of the Oct. 2 overtime thriller.

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49ers host Matthew Stafford and the Rams in a key NFC West clash
Rams QB Matthew Stafford Gets Good News Before 49ers Game

49ers, John Lynch and Trade Deadline

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Kyle Shanahan reveals why 49ers were content not making trade deadline splash
Kyle Shanahan spoke to Matt Maiocco on "49ers Game Plan" about why San Francisco was content with not making a move at the 2025 NFL trade deadline.

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John Lynch breaks silence on 49ers’ inactivity at NFL trade deadline
John Lynch Gives Blunt Reason on 49ers’ Quiet Trade Deadline

Rams, 49ers

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The matchup that will decide if the 49ers beat the Rams in Week 10
When the San Francisco 49ers square off with the Los Angeles Rams, it will be Sean McVay and Kyle Shanahan, Puka Nacua and Christian McCaffrey, Davante Adams and George Kittle, but all eyes should be on the trenches, because the Los Angeles Rams' star pass rusher against the San Francisco 49ers' star left tackle will decide the game

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Where to watch 49ers vs. Rams: TV channel, live stream and preview for Week 10
Rams vs. 49ers 2025 Prediction, Odds, Picks - Nov 9

49ers' Brock Purdy to miss sixth straight start, could play backup role against Rams

SANTA CLARA, Calif. — Quarterback Brock Purdy will miss his sixth straight start for the San Francisco 49ers with a toe ...

49ers QB Mac Jones again gets starting nod for Rams game

While quarterback Brock Purdy slowly works his way back from injury, the 49ers will once again turn to Mac Jones as the ...
Niners Wire on MSN

49ers Week 10 injury report has status updates on QB, WR and 6 other players

The San Francisco 49ers' Week 10 injury report didn't have much good news for a handful of the team's starters.

5 San Francisco 49ers who need to step up to beat the Los Angeles Rams

The San Francisco 49ers have been underdogs three times already this year and have lost twice. Their only win was over the ...

'Get the f—k out my phone': Rams-49ers rematch is getting testy

In the case of Verse, that familiarity goes all the way back to college. Verse, Green, Bethune and Fiske played on 2022 and ...

49ers missing another defensive starter vs. Rams in NFC West showdown; Purdy won't start

The San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a knee ...

Is Brock Purdy playing vs. Rams? Latest injury update on 49ers QB

A young defense with lots of rookies or first-time starters lost stars Nick Bosa and Fred Warner for the entire season in ...

Robert Saleh sounds off on the 49ers benching two rookies

Robert Saleh comments on the 49ers benching rookies Marques Sigle and C.J. West and how it can be beneficial. Rookies are ...