Madness odds for UConn Huskies vs UCLA Bruins women's Final Four March Madness NCAA Tournament game for betting on Friday, April 4, 2025.

Walter Clayton Jr. and Florida ended UConn’s pursuit of a third straight national championship, with Clayton burying two key 3-pointers in the final three minutes of a scintillating 77-75 victory for the top-seeded Gators in the second round of the NCAA Tournament.

Florida’s Alex Condon made it 65-64 by making his first of two free throws with 1:52 remaining, and Florida got the rebound off his miss on the second, getting two more free throws by Clayton with 1:45 left for a 67-64 lead.

Madness picks, predictions, odds for UConn vs Florida second-round West Region game on Sunday, March 23, 2025. Who wins game?

The SportsLine Projection Model has revealed its Florida Gators vs. Connecticut Huskies picks for the second round of the 2025 NCAA Tournament on Sunday

The player pool at this year's Final Four shows there's more than one way to build a roster these days. The question is who did it best among the teams that are left.

In the late game, No. 1 USC is as an underdog against No. 2 UConn, led by star guard Paige Bueckers. The Trojans, despite losing star JuJu Watkins to a season-ending injury earlier in the tournament, managed to survive their Sweet 16 matchup against Kansas State. But UConn will provide a much stiffer test.

UConn, the two-time reigning NCAA champions who’ve endured a season of angst, survived Oklahoma, 67-59, in a tense first-round game Friday night at the Lenovo Center. The victory was UConn’s 13th consecutive win in the NCAA Tournament spanning the past three seasons.