Jay and Pamela have a rare condition called Osteogenesis Imperfecta type III. This condition and their experience living with it are explained.

In an exclusive interview with PEOPLE, Jay and Pamela — both born with osteogenesis imperfecta, or brittle bone disease — ...

TLC star Pamela Chavez praised fiancé Jay Manuel for being a comforting partner and credited him for the positive impact he's ...

The couple was born with osteogenesis imperfecta Type 3 (OI) and together have had over 400 bone fractures throughout their lives.

Jay Manuel and Pamela Chavez, the stars of TLC’s reality show Jay & Pamela, recently joked about their sex life and made sure fans knew that it was far from tame. “No vanilla sex for us,” Jay, 28, ...

National Policy for Rare Diseases 2021 addresses diagnosis and treatment, categorizing diseases and advocating for affordable ...

TLC stars Jay Manuel and Pamela Chavez are looking to prove Jay’s family wrong as they express their doubts that the couple ...

Jay and Pamela both have a rare genetic disorder, Osteogenesis Imperfecta Type 3, a condition that causes fragile bones. They ...

Jay & Pamela” want to get married and live on their own but the couple keeps running into obstacles. A new episode of “Jay & ...

Orbit Phase 3 study of setrusumab in osteogenesis imperfecta progressing toward second interim analysis, expected mid-2025 Alvelestat granted Orphan Designation by the European Commission for ...